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Similarly, intraplantar exendin 2029 (20 g) injection significantly increased the PWT in the von Frey test from 30 to 90 min compared with CAP (1.6 g) administration alone (Fig

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However, unlike Ozempic and Wegovys active ingredient, tirzepatide works on a second hormone receptor, GIP (glucose-dependent insulinotropic polypeptide), which some studies suggest is more effective than semaglutide for blood sugar control and weight loss