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If this occured, it could under-report the levels of polysulfide sulfane sulfur, thus in our experiments we minimised incubation with TCEP without capping agent

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The complexity of the system is illustrated by findings that systemic salicylate-induced hyperactivity in the IC depends on nitric oxide signaling within that structure, which is known to mediate NMDA receptor signaling, indicating that interventions could target points in the signaling cascade upstream or downstream of the receptor itself (Olthof et al., 2022)

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