3.2 Pharmacological management of osteoarthritis 3.2.1 Non-opioid analgesics, anti-inflammatory agents, and senescence/ferroptosis-targeted drugs Non-opioid analgesics, particularly non-steroidal anti-inflammatory drugs (NSAIDs), are the pharmacological mainstay for symptom control in OA, particularly in cases presenting with moderate to severe pain (Table 2)
Phenolic compounds induce ferroptosis-like death by promoting hydroxyl radical generation in the fenton reaction
10.2174/1381612826666200212114038 [DOI] [PubMed] [Google Scholar] 64.Brennan BP, Jensen JE, Hudson JI, Coit CE, Beaulieu A, Pope HG, et al
Avoid overcooking, which can significantly reduce the antioxidant content
Its fascinating, but its also horrifying. Stop laughing at theories of everything Creating a theory of everything isnt exactly easy, notes philosopher of science Sam McKee in the understatement of the year