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Clinical trials commonly used 4mg daily administered subcutaneously for 28 days

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Compared with the control group, the treated mice showed a 35% decrease in white adipose tissue mass and markedly reduced adipocyte size

This condition can cause gait disturbance, weakness, and altered proprioception, potentially leading to abnormal joint loading and secondary musculoskeletal pain

SQ delivery may help, because fat tissue has fewer blood vessels than muscle, leading to slower dispersion of B12