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Notably, this pro-tumorigenic effect was absent at a concentration of 50 nM, suggesting that the carcinogenic potential of liraglutide is concentration-dependent [18]

Altogether, our SwissKASH system shows that local S-palmitoylation of Go can cause its in-situ accumulation in the signaling-competent form, indicating that zDHHC selectivity and subcellular localization are key players in the substrate compartmentalization of the G protein, and potentially PMPs in general

It is not approved by any regulatory authority and has not been evaluated for safety or efficacy in humans

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Hao C., Xu Z., Xu C., Yao R

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