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The mutation of GLP-1 Phe 28 to Ala causes it to lose nearly all of its affinity (IC 50 : 0.27 nM357 nM), and Ile 29 mutation decreases the affinity notably (IC 50 : 0.27 nM25 nM), while Trp 31 , Leu 32 , and Val 33 mutations have little influence, showing that they may be merely subsidiary

11 They may also occur along the endocardial surfaces of the atria and ventricles or on the eustachian valve

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Injections may be given weekly or biweekly for a short period when levels are low or symptoms are present

This being said, the reccomended daily dose for injectable L-Carnitine is anywhere from 600mg-2,500mg a day.