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glp-1 bmi 25 Weight loss with medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans: Cell Reports Medicine Overview of GLP-1s

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Graefes Arch Clin Exp Ophthalmol 1989;227:348-354

Jun 2000;27(6):1365-72

Of significance is the fact that the thiazolidinedione (TZD) class of drugs used to treat the hyperglycemia of type 2 diabetes (see the next section) activate PPAR which in turn increases the level of activity of PGC-1