[1] Other rare side effects noted (mostly in older literature or high-dose use) include: polycythemia vera and peripheral vascular thrombosis in patients receiving repeated injections (though these associations are not well understood, they were listed in prior product literature as possible adverse events)
The Interplay of Oxidative Stress and Cobalamin in MS Management Oxidative stress, characterized by a discrepancy between the formation of reactive oxygen species (ROS) and the ability of antioxidant defenses to neutralize them, has been linked to the pathophysiology of MS by inducing inflammation, demyelination, and neurodegeneration [109]
LaFemina J, Qin LX, Moraco NH, Antonescu CR, Fields RC, Crago AM, et al
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