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Complexity in Patient Understanding and Compliance: Many patients struggle with foundational aspects of melasma treatment, such as effective photoprotection, proper sunscreen use, and understanding radiation sources like blue light, HEV, and infrared

Copper Toxicity: Although transdermal patches hardly ever cause copper toxicity, you should nevertheless take the recommended dosage as advised on the bottle

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MAS combined with backcrossing has proven effective in consolidating resistance genes, improving the durability of resistance (Sharma et al