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This science advisory outlines the rationale and evolving role of percutaneous mechanical aspiration (PMA) in right-sided infective endocarditis (RSIE), summarizes available evidence and procedural best practices, offers expert guidance on patient selection, device use, and safety, and highlights remaining knowledge gaps and research priorities

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Results from several groups have provided evidence supporting this role

Recommended PT-141 Dosage To ensure the safe and effective use of PT-141, it is important to follow the recommended dosage guidelines

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