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There is scarce evidence that mature erythrocytes could contain some members of the Bcl-2 family of proteins

Preclinical and clinical programs must therefore not only demonstrate that hydrogels act as spacers and local delivery vehicles, but also define how tumor intrinsic factorsnotably histologic subtype (squamous cell carcinoma (SCC) versus adenocarcinoma (AC)) and HPV statusmodify radiosensitivity and the therapeutic benefit gained from hydrogel-mediated radiosensitization (see Table 3)

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