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Our results show that glutathione efflux from hepatocytes results in high local concentrations of both glutathione and cysteine in liver sinusoids, which transforms the nanoparticle surface chemistry, reduces its affinity to serum protein and significantly alters its blood retention, targeting and clearance

2023 Dec 14;389(24):2221-2232

Information provided is for educational purposes only and has not been evaluated by the FDA