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To investigate the mechanism by which GHK decreased the expression of miR-339-5p, SH-SY5Y cells that had been simultaneously stimulated with GHK and hemin were subsequently treated with different concentrations of the p38 activator dehydrocorydaline

Systemic effects Systemic side effects from GHK-Cu injections are rare in research settings but have been documented

Besides being a potential source of more reactive free radicals via Fenton reaction, physiological generation of H 2 O 2 fulfills a second messenger role and can be transported across membranes by aquaporins, a family of proteins that act as peroxiporins (Sies, 2014)

The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice