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At the full 12mg maintenance dose, the majority experience some degree of nausea during the first few weeks, though this typically fades substantially by weeks 8-12 at that dose level

Insurance coverage for Zepbound (the weight management indication) has been inconsistent, with many commercial plans applying prior authorisation requirements and some government programmes excluding coverage for obesity medications entirely

Over time, the associated risk reduction continued to drop: At 7 years, GLP-1 users had an 87 percent lower risk

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