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Launched in 2011, Lark Health's platform has since grown to reach nearly 2 million people to support managing their diabetes, weight loss, hypertension and behavioral health needs

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In a small randomized crossover trial, daily 15mg of pioglitazone in CAPD patients (both with and without DM) showed improved insulin resistance, adipokine balance, with reduced markers of inflammation.40 In the diabetic PD population, pioglitazone may be continued without any dose adjustments on PD-free days without increases risk of hypoglycemia.24 The main drawback to its use is related to its adverse effect profile on fluid retention, meaning that it is usually an alternative to other agents with a better safety profile

As many as 3050% of depressed patients respond only partially to antidepressants, leaving them with substantial residual symptoms (Davis et al., 2021)