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Sci Adv 8(33):9134 Fortin SM et al (2023) The locus coeruleus contributes to the anorectic, nausea, and autonomic physiological effects of glucagon-like peptide-1

It was the first incretin-based peptide to generate widespread public attention, driven by large-scale clinical trial programs that studied its effects on body weight and metabolic parameters

Back Labhart, A (1978) 'Intuition, luck and misfortune in diabetes research', Diabetologia , 14, 353-58

Oral formulations provide an alternative for patients preferring pills, and HSA or FSA funds can cover all PlexusDx medications, reducing your out-of-pocket costs

In the Phase 2 obesity data the weight curve was still trending downward at 48 weeks, so a genuine plateau at a tolerated maintenance dose may simply reflect the body settling toward a new set point rather than the protocol failing