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Following fixation in 4% paraformaldehyde (PFA), 5 dpf Brn3c:mGFP larvae, which express membrane-bound GFP in hair cells, were rinsed twice with phosphate-buffered saline (PBS) for 10 min each and then once with dH 2 o for 20 min

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Results We revealed that intracellular BPC157 engages the E3 ubiquitin ligase adaptor protein FBXO22 through its proline residue at position 3

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& Stein, S

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For instance, antispasmodic drugs (mainly anticholinergics) and antidiarrheal agents are used for abdominal pain and diarrhea

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