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Common concerns are disruptions in blood sugar control, changes in insulin sensitivity and risk of hypoglycemia
Will improvement in cardiovascular outcomes even be sufficient to reassure patients and payers on the value proposition of these drugs
In some embodiments, the gel is a solvent release gel such that the desired gel properties are formed after administration to or near the targeted auris structure, that is, as the solvent in the injected gel formulation diffuses out the gel, a gel having the desired gel properties is formed
Whether similar outcomes apply during active GLP-1 therapy hasn't been directly studied
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