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12.2 Pharmacodynamics Sitagliptin In patients with type 2 diabetes mellitus, administration of sitagliptin led to inhibition of DPP-4 enzyme activity for a 24-hour period

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In systemic lupus erythematosus (SLE), which is characterized by chronic activation of self-reactive lymphocytes and myeloid cells, untargeted lipidomics using LC/MS and GC/MS has revealed altered serum concentrations of choline, ACh, phosphocholine, and specific species of PC, lysoPC, and sphingomyelin (192194)

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