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Cardiovascular risk reduction alongside weight loss: Semaglutide
Ratka A, Sutanto W, Bloemers M, de Kloet ER
No Phase 3 trials were undertaken
That pairing isn't arbitrary these two compounds operate on different parts of the same axis and produce a growth hormone pulse that neither can generate alone with the same magnitude or quality
CVD Safety Semaglutide has a well-established FDA approval for reducing the risk of major adverse cardiovascular events (MACE) in high-risk patients, based on the SELECT trial which demonstrated a 20% reduction in MACE over a mean 39.8-month follow-up
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