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Contraindicaciones y precauciones importantes incluyen: Historia personal o familiar de carcinoma medular de tiroides o sndrome de neoplasia endocrina mltiple tipo 2 (contraindicacin absoluta) Pancreatitis aguda previa (usar con precaucin extrema) Enfermedad de la vescula biliar (puede aumentar el riesgo de colelitiasis y colecistitis) Enfermedad renal (no requiere ajuste de dosis, pero existe riesgo de lesin renal aguda si hay deshidratacin por efectos gastrointestinales) Retinopata diabtica (monitorear si existe retinopata previa, especialmente con mejora rpida de glucemia) Gastroparesia o trastornos severos de vaciamiento gstrico No est indicado para diabetes tipo 1 No recomendado durante el embarazo o lactancia Los efectos adversos gastrointestinales son los ms comunes, afectando hasta 30-50% de pacientes, especialmente durante la titulacin inicial

Potential candidates may include individuals seeking support for: Healthy Aging People interested in: Longevity optimization Biological age reduction Preventive medicine Health span enhancement Poor Sleep Quality Individuals experiencing: Fragmented sleep Age-related sleep decline Circadian rhythm disruption Recovery and Regeneration Those seeking support for: Cellular repair Recovery capacity Physical resilience High Oxidative Stress People exposed to: Chronic stress Environmental toxins Metabolic dysfunction Accelerated aging processes Longevity and Biohacking Programs Epitalon is increasingly incorporated into physician-guided longevity protocols focused on: Biological age optimization Cellular health Mitochondrial support Anti-aging medicine Epitalon and Biological Age Chronological age reflects how many years you have lived

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J., OConnell, H

Brunel-Guitton C, Costa T, Mitchell GA, Lambert M