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Reduced-frequency alternatives are practitioner-derived, built on pharmacokinetic reasoning: GHK-Cu has a short circulating half-life, but its tissue remodeling effects are cumulative

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While GSH scavenges OH, 1 O2, and NO directly, it catalytically detoxifies hydrogen peroxides (H 2 O 2 ), OONO , and lipid peroxides by activation of glutathione peroxidases

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To understand the underlying mechanism behind You-Gui-Wans anti-asthma activity, in vivo intratracheal sensitization of BALB/c mice with Dermatophagoides pteronyssinus to induce chronic asthma was followed by You-Gui-Wan treatment before challenge