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The article says constipation is more common with semaglutide, while tirzepatide produces alternating patterns with more diarrhea reported

Nevertheless, the question of whether loss of lean body mass is an issue of concern remains open 65, 66, 67

Appetite Suppression: GLP-1 also acts on the brain to reduce appetite and curb cravings, leading to a natural reduction in calorie consumption

Consequently, more mechanistic studies are required to determine the effects of both an acute exercise bout and chronic training on the major regulators of carnosine content

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