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(2018) reported that SCFAs, particularly butyrate, regulate glucocorticoid receptor (GR) expression through HDAC inhibition, affecting HPA axis negative feedback regulation efficiency

L-lysine, an essential amino acid, is important for protein synthesis, supporting muscle health, and promoting collagen production for skin health

Liposomal glutathione is an advanced form of glutathione encapsulated in liposomes, tiny fat-like molecules that protect the glutathione from digestive enzymes

Fatty acids are derived from adipose tissue lipolysis or from triglycerides stored in chylomicrons and very-low density lipoproteins, where they are transported from the circulation into cells

Conclusions In summary, this study demonstrated that NAC supplementation significantly reversed endocrine-metabolic changes and improved ovarian tissue phenotype in LE-induced PCOS mice