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doi: 10.1021/acsbiomaterials.7b00023 139 MaurerMGresnigtMSLastAWollnyTBerlinghofFPospichRet al

Results We describe parenteral administration of OHCbl using a subcutaneous catheter together with a portable infusion pump in a home therapy setting in four pediatric patients with remethylation disorders, two patients with cblC, one patient with cblG, and one patient with cblE deficiency, in whom intramuscular injections were not or no longer feasible

Specifically, the uptake and processing of unknown antigens by DCs triggers an immune response

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