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The precautionary principle suggests delaying GLP-1 initiation until breastfeeding concludes, allowing mothers to focus on nursing without unnecessary medication exposure to infants

metformin, sulfonylureas, TZDs, etc.) address only one of the underlying pathophysiology - lowering postprandial glucose levels, but their safety profiles and side effects, such as weight gain and hypoglycemia, may present challenges and limitations in their clinical use

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Semaglutide : Also highly effective, helping patients achieve an average weight loss of 1520% when combined with lifestyle changes