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Women planning pregnancy should discontinue use at least 2 months before attempting conception, based on guidance for similar compounds

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Options include tapering the dose over 4-8 weeks, switching to a different GLP-1 compound, or adopting a microdose protocol to maintain appetite suppression at lower cost

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Intermittent fasting Caloric restriction and intermittent fasting increase BDNF expression, likely through metabolic stress pathways that trigger adaptive neuronal responses