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If you miss two or more consecutive doses , contact your prescribing clinician, as re-titration from a lower dose may be recommended to reduce the risk of gastrointestinal side effects

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In March 2026, Structure reported 44-week topline data from the ACCESS II Phase 2 study, showing placebo-adjusted weight loss of up to 16.3%, which the company described as the highest efficacy demonstrated among oral GLP-1 receptor agonists at that time point