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The rationale to examine the mPFC is based on emerging reports studying alcohol dependent effects on working memory and mPFC gene expression [23, 62, 63]

concerns about immunogenicity/impurities

nucleus basalis of Meynert, central gray (especially medial), amygdala, spinal cord, the bed nuclei of the stria terminalis, the shell of the nucleus accumbens and the dorsal raphe nuclei

Many of the peptides studied in modern peptide science are associated with cellular communication, tissue dynamics, inflammatory signaling pathways, and regenerative biological processes