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Materials and methods Animals and experimental design Nine-week-old male Fischer 344 rats (Charles River Laboratory, Japan), weighing from 180-200 g, were maintained at 23C, given standard laboratory chow and water ad libitum, and kept under a 12 h light (7:00-19:00)/12 h dark schedule

Stopping GLP-1R agonists preoperatively may lead to worsened glycaemia and metabolic instability

The normal response to infection results in a balance between these inflammatory molecules

Medicines and Healthcare Products Regulatory Agency (2022)

Within 8 weeks, his knee pain reduced by 70%, allowing him to return to full duty workouts