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We have not seen nor do we expect some negative secondary effects of GLP-1 pharmaceuticals such as a loss of muscle mass and negative cardiovascular events. It should be noted, however, that BioRestorative Therapies has not yet published data on ThermoStems tolerability in a peer-reviewed journal

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For context, CagriSema's GI rate was compared to its individual components: semaglutide alone and cagrilintide alone both had lower GI event rates than the combination, consistent with additive GI effects

The IP and development strategies of leading players reflect this broader therapeutic ambition