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[18] These analyses were exploratory and not primary endpoints of the trials

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The crystals stimulate neutrophils to release NETs, which then aggregate and entrap the crystals within the web-like structure of the NETs

In einzelnen Fllen knnen dennoch leichte Reizungen oder vorbergehende Rtungen auftreten vor allem dann, wenn die Konzentration hoch ist oder die Haut besonders sensibel reagiert