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Most peptides are degraded rapidly by gastric acid and intestinal proteases
Often spaced at least 30 minutes away from other intranasal products
Similarly, partial microglial deletion or inhibition of C-C motif chemokine ligand 5 signaling increases BBB leakage during the early phases of inflammation
We stress the importance of validation to verify the feasibility of combining RCT and RWD, for instance, in building an external control arm
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