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[28] [29] A critical limitation in interpreting available evidence is the difficulty distinguishing lipedema fat from concurrent obesity

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Dormandy JA, Charbonnel B, Eckland DJA et al (2005) Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial