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Stat Med 18 , 11011110 (1999)

Sub-99% material introduces unknown variables uncharacterized impurity peaks may have their own biological activity or confound assay readouts

Shanks, J

Each day, shed wake up gasping for air, her skin covered in angry red welts, her mind foggy and unfocused

Nonetheless, the aforementioned animal models, although extremely useful in investigating specific molecular mechanisms in the pathogenesis of ulcerative colitis, do not truly recapitulate disease as observed in patients, as IBD is a multifactorial disease and most clearly is not caused by a single mutation or defect in cellular or molecular pathways