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Archived from the original on 24 September 2013

a low ratio decreases IL-12 secretion which favors a Th2 response pattern over Th1 (a condition typically associated with chronic inflammation), while an elevated ratio favors a Th1 response ( The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation

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The pharmacological blockage of SGLT-1 with phloridzin, in a rat small intestine perfused system, results in just a halved secretion of GIP, GLP-1, or PYY, and the addition of phloretin, a GLUT2 inhibitor, brings these values down to basal levels