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In this article, we review the history of DSIP, discuss what researchers currently understand about how it may work, and highlight the limitations of existing research

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And so, I look at that not so much as something I worry about, but something I'm really curious about

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From our point of view, when this whole system becomes altered-whether obesity, genetics or environmental factors act to disrupt its symphony-insulin resistance, steatosis, MetS, and ultimately T2D may develop