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The search was completed on August 15, 2023, and limited to English-language documents published since January 1, 2018

9,10 Additionally, some proponents for the use of Wegovy for obesity treatment posit that it is essentially the same medication as Ozempic, just in a different pen device which allows for delivery of higher doses

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Moreover, it downregulates the protein levels of cell proliferation marker PCNA, decreases cell viability and number, and upregulates the protein levels of pro-apoptotic markers [91]

Notably, the G/D-CuP group showed the lowest ratio of CD86-positive macrophages/CD206-positive macrophages, indicating an enhanced M1-to-M2 transition (Supplementary Fig