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However, in GCLM KO mice, genes encoding lipid synthesis enzymes, Fasn and Scd , were further down-regulated, whereas Fads1 was up-regulated by ethanol, the net effect of which would be expected to result in lower levels of total TG and increases in the relative abundance of certain lipid species

Limited Oral Options: Although oral GLP-1 receptor agonists have been developed, they are not yet widely available and may not be suitable for all patients