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Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB

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Additionally, it was found that GDH inhibition through siRNA resulted in a marked decrease in the proliferation of glioblastoma cells that were glutamine dependent [18, 90]

Although ferroptosis was first described in cancer cells [10] and its role in cancer biology is well established [11], its relevance has been extended to other diseases such as neurodegeneration, ischemia, and immune disorders [5]

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