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doi: 10.1172/jci.insight.9309893098 200 MichelLHelfrichIHendgen-CottaUBMincuRIKorsteSMrotzekSMet al

Research has examined how glucagon receptor activation contributes to energy expenditure, hepatic lipid metabolism, and thermogenesis and crucially, how these effects interact with simultaneous GLP-1R and GIPR activation, a research question unique to tri-agonist compounds

For type 2 diabetes, obesity, and weight management, GLP-1 receptor agonists are medications that may benefit your current treatment routine

Specifically, decreases in the activities of enzymatic antioxidants such as glutathione (GSH), SOD, CAT, and glutathione peroxidase (GPx) have been reported [156, 157]

King recommends patch testing if you have very sensitive or eczema-prone skin to ensure you don't have any unwanted reactions