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The primary objective of their investigation was to explore whether synthetic conformational constraints could replace the intricate disulfide bond bridging network in the -KIIIA conotoxin peptide, resulting in more stable analogues that retained bioactivity against human VGSCs

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10.2147/DNND.S299589 10 AmoahV.AtawuchugiP.JibiraY.TandohA.OsseiP