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Every experiment was repeated at least three times, and representative data are shown

Gastrointestinal Tract (GIT) and Food Intake In the GIT, GLP-1 reduces gastric motility, inhibits postprandial gastric acid secretion, decreases postprandial pancreatic exocrine secretion and reduces smooth muscle activity in the small intestine, 194 promoting a slower digestion of nutrients from the GIT

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Mechanistically, SLC25A39 loss impaired mitochondrial oxidative phosphorylation, increased reactive oxygen species (ROS), and triggered apoptosis

In 2023, it expanded into prescription weight-loss medications, adding GLP-1s to the mix while keeping its education-first foundation intact