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These symptoms suggest your body isn't eliminating toxins properly

The limited effectiveness of lifestyle changes alone increases the need for effective, long-term treatment for those with a body mass index (BMI) greater than 30 kg per m 2 or BMI of 27 kg per m 2 or greater with associated complications (e.g., hypertension, diabetes mellitus, and hyperlipidemia)

Patients should be educated about gradual dose titration to minimize gastrointestinal side effects

Your pre-operative instructions will tell you exactly which supplements to pause and when