issues with glp 1 Insights from Specialty Physicians on GLP-1RA Medications Off-Label Use Adverse effects of GLP-1 class

2 CKD confirmatory secondary endpoints Significant 18% RRR of MACE with Ozempic 2 For adults with T2D and CKD, for a confirmatory secondary endpoint: Time to first occurrence of MACE (CV death, nonfatal MI, or nonfatal stroke) vs placebo when both were added to standard of care 1,2 Time to first MACE 1-3,w-z 1-3,w-z w Cumulative incidence estimates are based on time from randomization to first EAC-confirmed MACE with non-CV death modelled as a competing risk using the Aalen-Johnson estimator

Adding a significant dose of fiber on top of that adaptation process is a recipe for discomfort

On the carnivore diet, fullness is also reinforced by whats missing: salty snacks, sugary drinks, and ultra-processed foods

Holst suspects this may help explain how GLP-1 agonists influence organs that lack direct receptor expression, including parts of the central nervous system

NAION occurs when blood flow to the optic disc is blocked, causing swelling which could lead to vision loss