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For the dipeptide exchange, 50 L of wild-type pHLA-I-P2FV [1M] was first incubated with the dipeptide (glycyl-valine GV or glycyl-leucine GL) at a 20-fold molar excess (1:20) overnight at RT

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Therefore, this study provided the first evidence of functional GLP-1R expression in human iTreg cells, and suggested that GLP-1R might play a key role in the anti-inflammatory effects attributed to GLP-1RA

doi: 10.3390/nu13030846 121 van der ArkK

A similar effect on visfatin was observed in other studies that showed that GLP-1 induced secretion of visfatin into the culture medium of 3T3-L1 adipocytes due to increased visfatin mRNA expression [35]