Glucuronidation also contributes to ochratoxin A detoxification, so UGT variants may have an overlapping impact across several mycotoxins.[ref] Related article: Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance Patulin and glutathione-dependent pathways: Patulin, a mycotoxin most commonly found in moldy apples and apple juice, binds to thiol groups in glutathione, depleting this key intracellular antioxidant and triggering oxidative stress and mitochondrial dysfunction
Avoiding excessive alcohol consumption is advisable as alcohol can deplete glutathione levels, impairing its protective functions in the body
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