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Sprague et al, 2008), while RL13 expression is lost in HCMV laboratory strains due to rapid mutations in the gene upon virus culture (Dargan et al, 2010

R 3 is C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkyl-OR S , optionally substituted C 1 -C 6 alkylC 3 -C 6 cycloalkyl, optionally substituted C 2 -C 7 heterocycloalkyl, C 1 -C 6 alkyl-CO 2 R 6 , C 1 -C 6 alkyl-C(O)NR 5 R 6 , or R 2 and R 3 together with the nitrogen to which they are attached form an optionally substituted C 2 -C 7 heterocycloalkyl ring

So steht das Molekl der Phase II sofort zur Verfgung, ohne auf eine ausreichende Versorgung mit Cofaktoren angewiesen zu sein (11, 13)

To model Leydig cell senescence in vitro, TM3 mouse Leydig cells were treated with hydrogen peroxide (H2O2)

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