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Also, as an anabolic hormone, insulin promotes fat storage, and chronic hyperinsulinemia, commonly observed in T2DM, further stimulates lipogenesis while suppressing lipolysis, thereby counteracting BW reduction

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Semaglutide should be used cautiously for people on other blood sugar-lowering medications

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In addition to the common core mechanisms for regulating the balance of Th17/Treg, several treatment methods discussed in this article involve the same signaling pathways, which are summarized in Table 11