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10.1152/physrev.00015.2012 16

Optimal dosing varies based on body weight, body composition goals, and individual metabolic factors

In the early phase of treatment, slowed gastric emptying increases physical fullness after meals, naturally reducing portion sizes without the need for strict calorie counting

Glutamate is then catalyzed by glutamate dehydrogenase (GDH) or glutamate transaminase, or aspartate transaminase (TAs) to produce -ketoglutarate (-KG)

The lipotropic pathway activates fat mobilisation over days to weeks, not hours